⚡ Polyneuropathy Case Studies

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Polyneuropathy Case Studies

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Polyneuropathy, Multifocal Motor \u0026 Diabetic Neuropathy – Neuropathology - Lecturio

ISSN PMC PMID British Medical Journal. Torpy; Jennifer L. Kincaid; Richard M. Glass 21 April Journal of the American Medical Association. National Institute of Neurological Disorders and Stroke. Textbook of Family Medicine. Elsevier Health Sciences. The chemotherapy source book 4th ed. Philadelphia, Pa. Frontiers in Neuroscience. Clinical neurology. London: Manson.

Pathology: Implications for the Physical Therapist. May Neurologic Clinics. Biologics: Targets and Therapy. BMJ Best Practices. Archives of Neurology. Neural Regeneration Research. Patient UK : Polyneuropathy. Diseases relating to the peripheral nervous system. Carpal tunnel syndrome Ape hand deformity. Ulnar nerve entrapment Froment's sign Ulnar tunnel syndrome Ulnar claw. Nearly all patients had complete resolution of symptoms. Patients who receive higher total doses may be at higher risk of peripheral neuropathy, but symptoms resolve after discontinuation of therapy in most patients.

Keywords: Antimicrobial stewardship; Metronidazole; Peripheral neuropathy. Smoked medicinal cannabis for neuropathic pain in HIV: a randomized, crossover clinical trial. Treatment of a hyperkinetic movement disorder during pregnancy with dronabinol. Effect of Delta 9 -tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower oesophageal sphincter relaxations in dogs and humans.

Psychopathological and cognitive effects of therapeutic cannabinoids in multiple sclerosis: a double-blind, placebo controlled, crossover study. Participants rated cannabis as similar effective as other medications for the treatment of their symptoms. Systemic bioavailability of the cannabinoid CRA13 increased by more than 4-fold if taken together with a fat-rich meal. Intermittent marijuana use is associated with improved retention in naltrexone treatment for opiate-dependence. Synthetic deltatetrahydrocannabinol dronabinol can improve the symptoms of schizophrenia. Improvement in 4 of 6 participants, of whom 3 showed a significant improvement. Lack of effect of cannabis-based treatment on clinical and laboratory measures in multiple sclerosis. White matter integrity in adolescents with histories of marijuana use and binge drinking.

Brain damage was less in alcohol users who used also cannabis than in alcohol only users. Characteristics of patients with chronic pain accessing treatment with medical cannabis in Washington State. A population-based case-control study of marijuana use and head and neck squamous cell carcinoma. Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosis. The study provides objective neurophysiological evidence that cannabinoids modulate the nociceptive system.

Use of medical marijuana for treatment of severe intractable nausea after laparoscopic Roux-en-Y gastric bypass surgery: case report. Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study. Evaluation of oral cannabinoid-containing medications for the management of interferon and ribavirin-induced anorexia, nausea and weight loss in patients treated for chronic hepatitis C virus. Improvement of appetite and reduction of nausea and vomiting by nabilone and dronabinol THC.

Adjunctive nabilone in cancer pain and symptom management: a prospective observational study using propensity scoring. Current status of cannabis treatment of multiple sclerosis with an illustrative case presentation of a patient with MS, complex vocal tics, paroxysmal dystonia, and marijuana dependence treated with dronabinol. Lack of analgesia by oral standardized cannabis extract on acute inflammatory pain and hyperalgesia in volunteers.

The cannabinoid receptor agonist nabilone for the treatment of dementia-related agitation. Dramatic reduction in the severity of agitation and other behavioural symptoms. Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy. Nabilone for the treatment of paraneoplastic night sweats: a report of four cases. A prospective identification of neuropathic pain in specific chronic polyneuropathy syndromes and response to pharmacological therapy. Similar treatment effects and side effects of cannabinoids compared to other medications. Open-label, add-on study of tetrahydrocannabinol for chronic nonmalignant pain.

Marijuana: an effective antiepileptic treatment in partial epilepsy? A case report and review of the literature. Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers. A medium dose of cannabis reduced pain, while a high dose increased pain induced by capsaicin. Sativex successfully treats neuropathic pain characterised by allodynia: A randomised, double-blind, placebo-controlled clinical trial. Anorexia of aging in long term care: is dronabinol an effective appetite stimulant? Dronabinol and marijuana in HIV-positive marijuana smokers: caloric intake, mood, and sleep.

Efficacy of dronabinol alone and in combination with ondansetron versus ondansetron alone for delayed chemotherapy-induced nausea and vomiting. Dronabinol was as effective as ondansetron in reducing nausea and vomiting. Combination therapy was not more effective. Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis. Cannabis in painful HIV-associated sensory neuropathy: A randomized placebo-controlled trial.

Smoked cannabis was well tolerated and effectively relieved chronic neuropathic pain from HIV-associated sensory neuropathy. THC reduced intraoculat pressure and improved blood circulation in the retina. Significant reduction of pain and improvement of quality of life with nabilone. Medicinal cannabis does not influence the clinical pharmacokinetics of irinotecan and docetaxel.

The effect of extreme marijuana use on the long-term course of bipolar I illness: a single case study. Cannabis decreased the number of depressed days and increased the number of hypomanic days. Long term marijuana users seeking medical cannabis in California : demographics, social characteristics, patterns of cannabis and other drug use of applicants. The treatment of spasticity with Delta 9 -tetrahydrocannabinol in persons with spinal cord injury. Spasticity of patients who received cannabis and complied with the study protocol was significantly reduced compared to placebo. The synthetic cannabinoid nabilone improves pain and symptom management in cancer patients. Synergistic affective analgesic interaction between deltatetrahydrocannabinol and morphine.

There was a synergistic effect between THC and morphine on the affective component of pain but not on the sensory component. Application of THC reduced the need of an opioid to treat postoperative pain but the difference to placebo was not significant. Dronabinol reduces signs and symptoms of idiopathic intracranial hypertension: a case report. Reduction in night-time agitation in actigraphy and in the neuropsychiatric inventory NPI.

A multicenter dose-escalation study of the analgesic and adverse effects of an oral cannabis extract Cannador for postoperative pain management. The optimal dose was 10 mg Cannador, effectively reducing postoperative pain without serious side effects. A pilot clinical study of Delta 9 -tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. THC was well tolerated in this pilot study of intrakranial cannabinoid administration. DeltaTHC based monotherapy in fibromyalgia patients on experimentally induced pain, axon reflex flare, and pain relief.

Five of the nine patients withdrew from the study due to side effects. Four patients experienced significant pain relief. Comparison of orally administered cannabis extract and deltatetrahydrocannabinol in treating patients with cancer-related anorexia-cachexia syndrome: a multicenter, phase III, randomized, double-blind, placebo-controlled clinical trial from the Cannabis-in-Cachexia-Study-Group. Topical application of a cream with N-palmitoyl ethanolamine had a good antipruritic effect in most patients.

Nabilone caused a significant reduction in pain and improvement of quality of life. Low dose treatment with the synthetic cannabinoid Nabilone significantly reduces spasticity-related pain : A double-blind placebo-controlled cross-over trial. Cannabinoids in the management of intractable chemotherapy-induced nausea and vomiting and cancer-related pain. Significant improvement in one case of intractable neuropathic pain and one case of refractory cinv. Preliminary assessment of the efficacy, tolerability and safety of a cannabis-based medicine Sativex in the treatment of pain caused by rheumatoid arthritis.

Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial. Survey of medicinal cannabis use among childbearing women: patterns of its use in pregnancy and retroactive self-assessment of its efficacy against 'morning sickness'. Postoperative nausea and vomiting was reduced by prophylactic administration of dronabinol and prochlorperazine. Effect of a cannabinoid agonist on gastrointestinal transit and postprandial satiation in healthy human subjects: a randomized, placebo-controlled study.

Cannabis use improves retention and virological outcomes in patients treated for hepatitis C. Long-term use of a cannabis-based medicine in the treatment of spasticity and other symptoms in multiple sclerosis. Evaluation of herbal cannabis characteristics by medical users: a randomized trial. Concurrent cannabis use during treatment for comorbid ADHD and cocaine dependence: effects on outcome. Moderate cannabis use had a positive effect of retention rates and abstinence from cocaine. Cannabinoids in multiple sclerosis CAMS study: safety and efficacy data for 12 months follow up. Spasticity in the Ashworth scale was significantly reduced by an average of 1.

Cannabis-based medicinal extract Sativex produced significant improvements in a subjective measure of spasticity which were maintained on long-term treatment with no evidence of tolerance. Beneficial effects of cannabis on spasticity in MS seem to be maintained over long-term treatment, with no evidence of tolerance. Smoked cannabis therapy for HIV-related painful peripheral neuropathy: results of a randomized, placebo-controlled clinical trial.

Randomized, controlled trial of cannabis-based medicine in central pain in multiple sclerosis. Cannabis is effective in reducing pain and sleep disturbance in patients with multiple sclerosis related central neuropathic pain. Marijuana use and its association with adherence to antiretroviral therapy among HIV-infected persons with moderate to severe nausea. Deltatetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction. THC is associated with transient exacerbation in core psychotic and cognitive deficits in schizophrenia. Efficacy and tolerance of the cream containing structured physiological lipids with endocannabinoids in the treatment of uremic pruritus: a preliminary study.

Clinical improvement and reduction of immunosuppressive drug therapy in cannabis treated patients with crohn's disease. There were no significant effects of cannabinoids on the cytokine profiles examined. Efficacy of two cannabis based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial. Cannabis for dyskinesia in Parkinson disease: a randomized double-blind crossover study.

Survey on cannabis use in Parkinson's disease: subjective improvement of motor symptoms. Does the cannabinoid dronabinol reduce central pain in multiple sclerosis? Randomised double blind placebo controlled crossover trial. Do cannabis-based medicinal extracts have general or specific effects on symptoms in multiple sclerosis? A double-blind, randomized, placebo-controlled study on patients. Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy. Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study.

An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis. Urinary urgency, the number and volume of incontinence episodes, frequency and nocturia all decreased. Initial experiences with medicinal extracts of cannabis for chronic pain: results from 34 'N of 1' studies. Effect of Deltatetrahydrocannabinol and cannabidiol on nocturnal sleep and early-morning behavior in young adults. Cannabis improves night vision: A pilot study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif Mountains of Northern Morocco.

A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms. Impaired bladder control, muscle spasms and spasticity were improved by cannabis in some patients. Short-term effects of cannabinoids in patients with HIV-1 infection: a randomized, placebo-controlled clinical trial. Randomised controlled trial of cannabis based medicinal extracts CBME in central neuropathic pain due to multiple sclerosis.

Efficacy of two cannabis-based medicinal extracts for relief of central neuropathic pain from brachial plexus avulsion: results of a randomised controlled trial. Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial. The effects of smoked cannabis in painful peripheral neuropathy and cancer pain refractory to opiods. Delta 9-tetrahydrocannabinol THC is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial. Lack of analgesic efficacy of oral deltatetrahydrocannabinol in postoperative pain. Cannabinoids for treatment of spasticity and other symptoms related to multiple sclerosis CAMS study : multicentre randomised placebo-controlled trial.

No effect of cannabinoids on spasticity as measured by the Ashworth scale, while patient-reported spasticity and pain decreased. THC reduced pain with low side effects; nabilone caused strong psychic side effects. The analgesic effect of oral deltatetrahydrocannabinol THC , morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions. Histamine induced responses are attenuated by a cannabinoid receptor agonist in human skin. A topically applied cannabinoid receptor agonist HU reduced pain caused by capsaicin. Dronabinol versus megestrol acetate versus combination therapy for cancer-associated anorexia: a North Central Cancer Treatment Group study.

Treatment of Tourette's syndrome with Delta 9-tetrahydrocannabinol THC : a randomized crossover trial. Significant improvement of tics and obsessive-compulsive behavior after treatment with THC. Randomised, double-blind, placebo-controlled trial to assess the potential of cannabinoid receptor stimulation in the treatment of dystonia. Compared with placebo, neither THC nor plant-extract treatment reduced spasticity.

Preliminary observation with dronabinol in patients with intractable pruritus secondary to cholestatic liver disease. A casuistic rationale for the treatment of spastic and myocloni in a childhood neurodegenerative disease: neuronal ceroid lipofuscinosis of the type Jansky-Bielschowsky. Russo, M. Mathre, A. Byrne, R. Velin, P. Bach, J. Sanchez-Ramos, K. Cannabis was the most effective and readily available therapy to quit cocaine use.

Combined treatment of Tourette syndrome with deltaTHC and dopamine receptor agonists. Cannabinoids reduce levodopa-induced dyskinesia in Parkinson's disease: a pilot study. Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac. Clinical investigation of deltatetrahydrocannabinol THC as an alternative therapy for overactive bladders in spinal cord injury SCI patients. Effects of smoked cannabis and oral deltatetrahydrocannabinol on nausea and emesis after cancer chemotherapy: A review of state clinical trials. Hemp for headache: An in-depth historical and scientific review of cannabis in migraine treatment.

Antinociceptive, subjective and behavioral effects of smoked marijuana in humans. There was no effect on daily incontinence, but the cannabis extract was superior to placebo for nocturia. Analgesic effect of the cannabinoid analogue nabilone is not mediated by opioid receptors. Cannabis use helped patients to quit crack use by reducing the craving symptoms. The use of cannabis as a mood stabilizer in bipolar disorder: anecdotal evidence and the need for clinical research. A number of patients find cannabis marihuana useful in the treatment of their bipolar disorder. Cannabinoids: possible role in patho-physiology and therapy of Gilles de la Tourette syndrome.

Activation of cannabinoid receptors can reduce L-DOPA-induced dyskinesia in man without aggravating parkinsonism. Smoking cannabis stopped hiccups that did not respond to usual medications on the 8th day. Intractable nausea and vomiting due to gastrointestinal mucosal metastases relieved by tetrahydrocannabinol dronabinol. Long-term efficacy and safety of dronabinol for acquired immunodeficiency syndrome-associated anorexia. The safety and pharmacokinetics of single-agent and combination therapy with megestrol acetate and dronabinol for the treatment of HIV wasting syndrome.

Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease. Marijuana to prevent nausea and vomiting in cancer patients: a survey of clinical oncologists. The effect of orally and rectally administered deltatetrahydrocannabinol on spasticity: a pilot study with 2 patients. Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS. Treatment of spasticity in spinal cord injury with dronabinol, a tetrahydrocannabinol derivative. A phase II study of deltatetrahydrocannabinol for appetite stimulation in cancer-associated anorexia.

Short-term effects of smoking marijuana on balance in patients with multiple sclerosis and normal volunteers. Nabilone and metoclopramide were equally effective in reducing nausea and vomiting. Dronabinol and prochlorperazine in combination for treatment of cancer chemotherapy-induced nausea and vomiting. Marijuana as antiemetic medicine: a survey of oncologists' experiences and attitudes. Deltatetrahydrocannabinol shows antispastic and analgesic effects in a single case double-blind trial. Patients continued to loose, but the weight loss decreased in all groups; appetite and mood increased.

Efficacy of tetrahydrocannabinol in patients refractory to standard anti-emetic therapy. Effects of smoked marijuana on food intake and body weight of humans living in a residential laboratory. Increases in body weight during periods of active marijuana smoking were greater than predicted by caloric intake alone. A randomized trial of oral nabilone and prochlorperazine compared to intravenous metoclopramide and dexamethasone in the treatment of nausea and vomiting induced by chemotherapy regimens containing cisplatin or cisplatin analogues.

The patients notes a significant amelioration of symptoms when smoking cannabis. DeltaTHC in the treatment of spasticity associated with multiple sclerosis. Nabilone versus prochlorperazine for control of cancer chemotherapy-induced emesis in children: a double-blind, crossover trial. A double-blind randomised cross-over comparison of nabilone and metoclopramide in the control of radiation-induced nausea. The administration of two or three active marijuana cigarettes during the social access period increased average daily caloric intake. Nabilone and metoclopramide in the treatment of nausea and vomiting due to cisplatinum: a double blind study. Even for young children nabilone is an effective antiemetic, superior to domperidone. Crossover comparison of the antiemetic efficacy of nabilone and alizapride in patients with nonseminomatous testicular cancer receiving cisplatin therapy.

Prospective randomized double-blind trial of nabilone versus domperidone in the treatment of cytotoxic-induced emesis. DeltaTHC proved clinically beneficial in two of five patients with intractable spasticity. Part II: Patient drug preference. A cross-over comparison of nabilone and prochlorperazine for emesis induced by cancer chemotherapy. Beneficial and adverse effects of cannabidiol in a Parkinson patient with sinemet-induced dystonic dyskinesia. Antiemetic efficacy of levonantradol compared to deltatetrahydrocannabinol for chemotherapy-induced nausea and vomiting. Levonantradol appears to be at least as effective an antiemetic as THC ; well-tolerated side-effects. Antiemetic therapy: a review of recent studies and a report of a random assignment trial comparing metoclopramide with deltatetrahydrocannabinol.

Poorer antiemetic control and more side effects with dronabinol than with the metoclopramide, both better than placebo. Randomized double blind comparison of deltatetrahydroicannabinol THC and marijuana as chemotherapy antiemetics. Dose ranging evaluation of the antiemetic efficacy and toxicity of intramuscular levonantradol in cancer subjects with chemotherapy-induced emesis. An initial evaluation of Nabilone in the control of radiotherapy-induced nausea and vomiting. Tetrahydrocannabinol vs. The effects of two antiemetics on patients undergoing radiotherapy.

Comparison of bronchial effects of nabilone and terbutaline in healthy and asthmatic subjects. A double-blind trial of delta 9-tetrahydrocannabinol in primary anorexia nervosa. Anti-emetic efficacy and toxicity of nabilone, a synthetic cannabinoid, in lung cancer chemotherapy. Symptom scores were significantly better for patients on nabilone for nausea, retching and vomiting. Nabilone, in comparison with chlorpromazine did not significantly reduce the number of vomiting, but most patients preferred nabilone.

A randomised multicentre single blind comparison of a cannabinoid anti-emetic levonantradol with chlorpromazine in patients receiving their first cytotoxic chemotherapy. Cannabis and cancer chemotherapy: a comparison of oral deltaTHC and prochlorperazine. Randomised clinical trial of levonantradol and chlorpromazine in the prevention of radiotherapy-induced vomiting.

NCS are performed Rhonda Jacobs Research Paper Outline a physician specially trained in Polyneuropathy Case Studies. The association between cannabis use and suicidal behavior in patients with Polyneuropathy Case Studies disorders: an analysis of sex differences. Polyneuropathy Case Studies of the variability Polyneuropathy Case Studies severity and progression of the disease, Polyneuropathy Case Studies will not Polyneuropathy Case Studies able to give a definite prognosis. Trendelenburg's sign. Polyneuropathy Case Studies Parameter: Evaluation of distal Polyneuropathy Case Studies polyneuropathy: Role of autonomic testing, nerve biopsy, and skin biopsy an evidence-based review.

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